Journal du syndrome métabolique

Prevalence of Metabolic Syndrome and its Individual Components among Moroccan Adolescents: The Role of Overweight-Obesity and Excess Body Fat

Abstract

Abdeslam Hamrani, Slimane Mehdad, Khalid El Kari, Asmaa El Hamdouchi, Amina Barkat, Hakim Belghiti, Mohammed El Mzibri,Noureddine El Haloui, Najat Mokhtar and Hassan Aguenaou

Background: The prevalence of obesity and related diseases such as metabolic syndrome (MetS) are increasing in young populations over the world, especially in developing countries. This study aimed to estimate the prevalence of MetS and its individual components, and to assess their association with both overweight/obesity and excess body fat.

Methods: This study included 192 adolescents (77 boys and 115 girls) aged 11 to 17 years. Blood pressure and anthropometric measurements were done using standardized techniques. Fasting blood samples were taken for determination of glucose and lipids levels. Percent body fat was estimated using deuterium oxide. The international diabetes federation criteria were applied for the diagnosis of MetS.

Results: The prevalence of MetS among overweight/obese adolescents was 18.6% while it was not observed in their normal weight counterparts. The most common abnormality found in the study population was reduced HDLcholesterol (26.6%) followed by elevated fasting blood glucose (22.4%) and high waist circumference (19.3%). Among overweight/obese groups, the rates of individuals with raised TG and reduced HDL-cholesterol were significantly higher in boys than girls (35.0% vs. 15.2%, p=0.044; and 32.5% vs. 13.0%, p=0.038, respectively). Compared to normal-weight adolescents, overweight/obese subjects had higher odds of having at least two MetS components (OR=5.37, 95%CI: 2.72-10.59), or at least three MetS components (OR=11.80, 95%CI: 3.40-41.03). Excess body fat showed similar degrees of association with clustering MetS components.

Conclusions: The prevalence of MetS and its individual components was quite high among the study population, particularly among overweight/obese adolescents. MetS components were strongly associated with both overweight/ obesity and excess body fat. MetS and its components might be best predicted by obesity indexes, determined according to age and body mass index in adolescents, than accurate percent body fat.