Journal du syndrome métabolique

Leptin Resistance: The Silent Barrier to Weight Loss

Abstract

Luke Nathan*

Leptin resistance is a complex physiological condition characterized by reduced sensitivity to the hormone leptin, which plays a crucial role in regulating appetite and energy expenditure. This resistance can lead to disruptions in normal body weight regulation, potentially contributing to obesity and related metabolic disorders. This abstract provides an overview of leptin resistance, its underlying mechanisms and its implications for human health. Understanding leptin resistance is essential for addressing the global obesity epidemic and developing effective therapeutic strategies.