Journal des maladies infectieuses et de la médecine

Epigenetics\'s Function in Cardiovascular and Periodontal Diseases

Abstract

Maglio Urganci

Epigenetics, the study of heritable changes in gene expression that do not involve alterations to the DNA sequence itself, has emerged as a crucial field in understanding the pathogenesis of various diseases. This article explores the role of epigenetics in two distinct yet interconnected health conditions: Cardiovascular Diseases (CVD) and periodontal diseases (PD). Both diseases are influenced by a complex interplay of genetic, environmental and lifestyle factors, where epigenetic mechanisms provide a nuanced understanding of disease susceptibility, progression and potential therapeutic targets. This review highlights current research findings on epigenetic modifications such as DNA methylation, histone modifications and non-coding RNAs in the context of CVD and PD, underscoring their impact on gene regulation, inflammation and tissue remodeling. Furthermore, the article discusses the potential implications of epigenetic therapies in managing and preventing these prevalent and interrelated diseases.