Journal de néphrologie et thérapeutique

Upper Digestive Endoscopic Lesions in Chronic Kidney Disease (CKD): Experience of a Senegalese Center; About 50 Cases

Abstract

Cisse Mouhamadou Moustapha*,Ka El Hadji Fary,Dia Daouda,Mahamat AG,Jean De Dieu Nzambaza,Lemrabott Ahmed Tall,Fall Seynabou,Faye Maria,Fall Khodia,Bassene Marie Louise,Niang Abdou,Diouf Boucar

Objectives: This study was conducted to evaluate upper digestive endoscopic lesions among patients with chronic kidney disease.

Methodology: We conducted a retrospective cross-sectional study in Nephrology and Gastroenterology services at Hospital Center University Aristide Le Dantec from January 2008 to December 2009. All patients with chronic kidney disease who underwent an upper gastrointestinal endoscopy were included.

Results: Fifty patients were included, with a mean age of 44.2 years and a sex ratio (male/female) of 1.27. Upper digestive endoscopy was abnormal in 76%. Peptic esophagitis was noted in 7 patients, hiatal hernia in 10 and cardial incontinence in 2. Congestive gastritis was observed in 6 cases, followed by erosive and hemorrhagic gastritis in 5 cases each one and a gastric ulcer in 2. Six patients presented a bulbitis, which was erosive in 3, congestive in 2 and 1 of the large folds. Bulbar ulcer was noted in 3 patients and post bulbar ulcer was also noted in 3 patients. One patient presented a congestive duodenitis.

Conclusion: Upper digestive endoscopy lesions are frequent and diverse among patients with chronic kidney disease. These finding justify the systematization of upper digestive endoscopy in digestive complaining uremic patients.