Journal des complications et de la médecine du diabète

An Analysis of Curcumin, a Polyphenol Curcuminoid Preventive Properties and Molecular Processes in Diabetic Nephropathy

Abstract

Tervaert Cohen

Diabetic nephropathy is the most common cause of end-stage renal disease and has a significant impact not only on patients but also on society as a whole. Due to the limited availability of medical treatment, effective alternative therapeutic approaches for the treatment of Diabetic nephropathy are urgently required. Research on diabetic nephropathy has shown that curcumin, a polyphenol curcuminoid, has anti-inflammatory, anti-oxidative, anti-apoptotic, and anti-fibrosis properties. This review has gone over the clinical and preclinical trials, as well as the mechanisms by which curcumin affects Diabetic nephropathy. Curcumin's pharmacological effects on diabetic nephropathy may be better understood, which could lead to more effective treatments for the condition.