Médecine moléculaire et génétique

The Functions of Glial Cells and Epigenetics in Drug-induced Autism Spectrum Disorder

Abstract

Ethan Taylor

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by deficits in social communication and repetitive behaviors. While genetic factors play a significant role in ASD, emerging evidence suggests that environmental factors, including drug exposure during pregnancy, can also contribute to its etiology. Glial cells, once considered mere support cells in the brain, are now recognized as key players in neuronal function and neurodevelopment. Additionally, epigenetic mechanisms, such as DNA methylation and histone modifications, have been implicated in the pathogenesis of ASD. This article explores the functions of glial cells and epigenetic processes in drug-induced ASD, highlighting their interplay and potential therapeutic implications.