Revue des sciences chimiques

Organocatalysis: Unleashing the Power of Small Organic Molecules in Synthetic Chemistry

Abstract

Awad Andrew

Organocatalysis is a branch of catalysis that involves the use of small organic molecules, called organocatalysts, to accelerate chemical reactions. Unlike traditional catalytic processes that often employ transition metals or enzymes, organocatalysis relies on the reactivity of functional groups within organic molecules to activate substrates and facilitate transformations. The concept of organocatalysis dates back several decades, but it has gained significant attention and recognition in recent years due to its broad applicability and sustainable nature. Organocatalysis offers several advantages over other catalytic methods, including mild reaction conditions, high selectivity, and compatibility with a wide range of functional groups. Additionally, organocatalysts are often readily available, cost-effective, and have low toxicity, making them attractive for industrial applications.