Journal de pharmacognosie et de produits naturels

GC-MS Evaluation of Stem Bark Extract of Sterculia oblonga for Biomedical Potentials

Abstract

Patience Yake Nkom, Esther Offiong Asuquo, Lynius Ashipu Bebiaundeye and Endurance Egwu Ukam

The stem-bark of Sterculla oblonga, which is a rich lignocellulosic material, was analysed using GC-MS chromatography in other to identify the bioactive compounds present in the plant and deduce its possible therapeutic potentials. The pulverized plant sample was extracted by maceration for 48 hours using ethanol solvent, after solvent recovery, the crude extract was used for the GC-MS analysis. Results revealed the presence of 12 bioactive compounds namely: 1-(Butylsulfanyl)-2-ethoxyethane 4-methoxyphenol (mequinol), 2,6-dimethoxy-phenol (Syringol), 3,4,5-Trimethoxyphenol, 4,4,5,6-Tetramethyltetrahydro-1,3-oxazin-2-thione, n-Hexadecanoic acid (Palmitic acid), 1-Docosene, 14-methyl-8- hexadecen-1-ol, 1,19-Eicosadiene, Z-10-Tetradecen-1-ol acetate, 1-Nonadecene and Oleic Acid. These chemicals were further grouped into 5 viz organo-sulphur (2%), phenols (24%), alkaloids (2%), fatty acids/esters (22.18%) and hydrocarbons (8.66%). Because of the high percentage of phenolic compounds present, the ethanolic extract of stem-bark of S. oblonga could find useful therapeutic applications as antimicrobial, anticancer, anti-oxidant and anti-diabetic agents.