Médecine moléculaire et génétique

Durable, Strong and Broad-spectrum Ceria Nanoparticles Target Virion Surfaces to Inactivate RNA Virus Infectivity by Interfering with Virus-receptor Interactions

Abstract

Lars Andersen

Nanoparticles have garnered considerable interest in the field of antiviral therapeutics due to their unique properties and potential applications. Among these, cerium oxide (ceria) nanoparticles have shown promise as a novel antiviral agent, demonstrating durable, strong, and broadspectrum activity against RNA viruses. This paper explores the mechanism by which ceria nanoparticles target virion surfaces, leading to the inactivation of viral infectivity. By interfering with virus-receptor interactions, ceria nanoparticles disrupt crucial steps in the viral lifecycle, offering a promising avenue for the development of effective antiviral strategies.