Revue des sciences chimiques

Antimicrobial Assay of Newly Synthesised Copper Complex Derived from Tolylamine

Abstract

Lekha L and Kanmaniraja K

An attempt has been made to synthesise the Schiff base ligand (E)-4-bromo-2-((p-tolylimino)methyl)phenol by the condensation of tolylamine and 5-bromosalicylaldedhye and the coordination behavior its copper complex has been explored by various spectroscopic techniques like UV-Vis., IR, 1H NMR, MS and elemental analysis. The investigative information of the unpredictable demonstrates the arrangement of 1:2 Copper to ligand proportion with the formula [CuL2]. The ligand and the copper chelate have been screened for their antimicrobial activities utilizing disc dissemination technique against gram positive and gram negative bacterial species like Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia and parasitic species like Candida and Aspergillus .