Journal de gastroentérologie clinique

The Role of Gut Microbiota in Inflammatory Bowel Disease: Current Understanding and Future Directions

Abstract

Jennifer Ristagno*

Inflammatory Bowel Disease is a chronic inflammatory disorder of the gastrointestinal tract characterized by periods of relapse and remission. While the exact etiology of IBD remains elusive, it is increasingly recognized that the gut microbiota plays a crucial role in its pathogenesis. This review explores the current understanding of the intricate relationship between gut microbiota and IBD, focusing on microbial dysbiosis, mucosal immune response, and therapeutic implications. Furthermore, it discusses emerging research directions and potential future interventions targeting the gut microbiota for the management of IBD.