Médecine pulmonaire et respiratoire

Meigs Syndrome with Elevated CA 125: Case Report with a Journey through Literature

Abstract

Catia Isabel Ferreira da Silva Guimaraes, Sandra Afonso André and Fernando José Dias Nogueira

Meig’s syndrome is a rare syndrome that consists of a benign ovarian tumor accompanied by ascites and pleural effusion. Elevated serum carbohydrate antigen 125 (CA 125) levels in postmenopausal women with solid adnexal masses, ascites and pleural effusion are highly suggestive for malignant ovarian tumors.

Patients with Meig`s syndrome have a benign disease, with good prognosis, but can also have elevated serum CA 125 levels. The authors present a case report of Meig’s syndrome caused by a fibro thecoma with elevated CA 125 levels in a postmenopausal woman. That is a rare cause of pleural effusion, which is interesting because of its diagnosis and clinical course. The authors will also discuss the pathophysiology of this disease.