Journal de recherche translationnelle en oncologie

Leptin Resistance: Unraveling the Complex Web of Obesity and Metabolic Dysfunction on Cancer Patients

Abstract

Luke Nathan*

Leptin resistance is a complex physiological condition characterized by reduced sensitivity to the hormone leptin, which plays a crucial role in regulating appetite and energy expenditure. This resistance can lead to disruptions in normal body weight regulation, potentially contributing to obesity and related metabolic disorders. This abstract provides an overview of leptin resistance, its underlying mechanisms, and its implications for human health. Understanding leptin resistance is essential for addressing the global obesity epidemic and developing effective therapeutic strategies.