Journal de cytologie et d'histologie

Histological Study on the Potential Effect of Sildenafil on the Kidney and Testosterone Level in Experimentally Induced Diabetes in Male Rats

Abstract

Yousry Abd-Elkader M, Abas Farag E and Ibraheem Omar A

This study concluded that diabetes type I resulted in pronounced oxidative stress that affected renal function and structure and reduced testosterone level. Sildenafil administration for 8 weeks proved to have a potential renal protective capacity at both morphological and functional levels. Thus, Sildenafil might have a potential novel in restoration of kidney function and structure in diabetic male patient especially those with low testosterone level.