Médecine Nucléaire et Radiothérapie

Gamma Knife and Chemoradiotherapy Applied Nasopharyngeal Cancer Patient Observed Radiation-Induced Optic Neuropathy and Retinopathy: A Case Report

Abstract

Alsan Cetin I, Taka U, Sahin O, Ozen Z, Abac?oglu U and Kazokoglu H

Introduction: Radiotherapy is treatment for nasopharyngeal carcinoma, and concurrent chemoradiotherapy has been shown to prolong survival. Radiation-induced is a dramatic late complication of radiation therapy for tumors involving structures in the vicinity of the visual pathway. The association between dose and radiation retinopathy is well established. Case presentation: The patient was a 48-year-old turkish man. A case history of bilateral radiation-induced optic neuropathy and retinopathy, 105 months after combined treatment by chemotherapy, conformal radiotherapy and 62 months after gamma knife for a nasopharyngeal carcinoma. Conclusion: We recommend that all patients undergoing radiotherapy, which is likely to result in retinal irradiation, be warned of risk of radiation retinopthy of the dose applied.