Journal de neurologie clinique et de neurochirurgie

Evaluating the Efficacy of Novel Surgical Techniques in Treating Drug-resistant Epilepsy

Abstract

Merab Hirshman

Drug-resistant epilepsy presents a significant challenge in neurology and neurosurgery. Despite advancements in pharmacological treatments, a substantial proportion of patients experience persistent seizures that do not respond to conventional anti-seizure medications. For these individuals, surgical intervention offers a promising alternative. Epilepsy is a neurological disorder characterized by recurrent, unprovoked seizures resulting from abnormal electrical activity in the brain. While many patients achieve satisfactory seizure control with Anti-Seizure Medications (ASMs), a substantial subset of individuals, termed Drug-Resistant Epilepsy (DRE), continues to experience seizures despite treatment. Understanding drug-resistant epilepsy involves exploring its definition, causes, diagnostic challenges and impact on patients.