Biologie moléculaire : accès libre

Common Malignancies of the Genitourinary System

Abstract

Gareth Griffiths*

Renal cell carcinoma also known as kidney cancer is one of the most common malignancies of the genitourinary system. While early-stage RCC can often be successfully treated, advanced cases pose a significant clinical challenge due to their propensity for metastasis. Metastasis is the process by which cancer cells spread from the primary tumor site to distant organs and tissues. In the context of RCC, understanding the mechanisms and factors that drive metastasis is crucial for improving patient outcomes and developing targeted therapies. This article delves into the intricacies of metastasis in renal cell carcinoma, exploring its molecular basis, clinical implications, and current treatment strategies. Renal cell carcinoma is a malignant neoplasm that originates in the renal tubular epithelium. It accounts for approximately 2-3% of all adult malignancies, with a higher prevalence in males.