Journal de bioanalyse et de biomédecine

Characterization of Nanomaterials: Knowing How Nano-Bio Interactions Work

Abstract

Aliaa Amer

Despite their remarkable smallness, nanomaterials can be utilized to great effect. Over the past ten years, a lot has been learned about how nanomaterials affect biological interactions and effects. However, as-synthesized materials are typically used for nanomaterial characterization. We contend that nanomaterials ought to be studied and regulated as dynamic entities. As a result, biotransformation should be taken into account when characterizing nanomaterials. In nanosafety, however, in situ characterization of nanomaterials as they undergo dynamic changes in a living system (coronation, dissolution, degradation) remains a formidable obstacle. To address this issue, toxicologists and material scientists must collaborate.