Médecine pulmonaire et respiratoire

Acute Demyelinating Polyneuropathy Due to Sarcoidosis Mimicking Guillain-Barre Syndrome-A Case Report

Abstract

Dushantha Madegedara, Asela Rasika Bandara, Sachini Seneviratne, Sajani Dharmadasa and Samadara Nakandala

Sarcoidosis is an inflammatory granulomatous disease with diverse clinical manifestations. Neurological manifestations occur in minority which can mimic many other pathologies. Sarcoid peripheral neuropathy is a heterogeneous group comprising many different clinical patterns. Acute demyelinating type of polyneuropathy masquerading Guillain-Barre Syndrome (GBS) can rarely occur due to sarcoidosis. We report a 50 year old female with recent onset symptoms of sarcoidosis developing acute demyelinating polyneuropathy mimicking GBS. Distinction between both conditions is important for appropriate management. However, this can be challenging in clinical practice.