Journal de cytologie et d'histologie

A Flat Elevated Lesion of Well-differentiated Adenocarcinoma with Lymphoid Stroma of the Colon

Abstract

Hideaki Harada, Satoshi Suehiro, Takanori Shimizu, Masatoshi Hashimoto, Yasushi Katsuyama and Kenji Hayasaka

Here, we present a rare case of a 78-year-old male with well-differentiated adenocarcinoma with lymphoid stroma of the colon. Colonoscopy revealed a type 0-IIa-like lesion located at the descending colon. We performed endoscopic submucosal dissection of the lesion. Histological examination of the resected specimen revealed that the tumor was comprised of well-differentiated adenocarcinoma with lymphoid cell infiltration accompanied by submucosal lymphoid follicle formation. Because of a positive for vertical resection margin, we performed an additional surgical resection. However, we found no residual tumor or lymph node metastases. To the best of our knowledge, this is a rare report describing a case of dome-type carcinoma with lymphoid stroma of the colon for which magnifying endoscopy with crystal violet staining and narrow-band imaging was performed.