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Volume 9, Problème 2 (2023)

Mini-revue

Clinical Assessment of the Oral Cavity in Mental Patients with Dietary Problems

Lorenzo Shao*

This study aims to explore the clinical assessment of the oral cavity in mental patients with dietary problems. Mental health disorders often coexist with dietary issues, leading to adverse oral health outcomes. The objective of this research is to evaluate the oral health status of individuals with mental health conditions and identify any associations between dietary problems and oral health complications. A comprehensive clinical assessment was conducted, including dental examinations, assessment of dietary habits, and interviews with mental health professionals. The findings indicate a significant correlation between mental disorders and poor oral health, particularly in patients with dietary problems. The results emphasize the importance of integrated care approaches that address both mental health and oral health in this vulnerable population.

Mini-revue

Elevated L−aminoisobutyric Acid Aids to the Pathophysiology of Treatment−Resistant Schizophrenia and Clozapine Adverse Effects

Damian Fukuyama

This study aims to investigate the potential role of enhancing L-Aminoisobutyric Acid (LAIBA) in the pathophysiology of Treatment-Resistant Schizophrenia (TRS) and its effect on the adverse effects of clozapine. TRS is a challenging form of schizophrenia characterized by a lack of response to conventional antipsychotic medications, including clozapine, which is often prescribed as a last resort. Recent evidence suggests that alterations in neurotransmitter systems, including glutamatergic dysfunction, may contribute to TRS. LAIBA, a non-proteinogenic amino acid, has been shown to modulate glutamatergic transmission. In this study, we investigated the effects of LAIBA on TRS and the adverse effects associated with clozapine treatment in an animal model. Our findings suggest that enhancing LAIBA levels may have therapeutic potential in TRS by regulating glutamatergic signaling and ameliorating the adverse effects of clozapine. Further research is warranted to explore the underlying mechanisms and evaluate the translational potential of LAIBA supplementation in TRS.

Mini-revue

Healthcare Workers′ Mental Health during the COVID−19 Pandemic: Long−Term Trends and Risk Factors

Sara Colombo*

This study aims to examine the long-term trends and risk factors associated with healthcare workers' mental health during the COVID-19 pandemic. The unprecedented challenges faced by healthcare professionals during this global crisis have taken a toll on their mental well-being. The objective of this research is to analyze the evolving patterns of mental health among healthcare workers over an extended period and identify the factors that contribute to their psychological distress. Through a comprehensive review of existing literature and empirical data, this study sheds light on the long-term effects of the pandemic on healthcare workers' mental health and provides insights into the risk factors that need to be addressed to support their well-being.

Mini-revue

Examining the Variables: Post-Mortem Dismemberment Cases and the Insanity Defense

Samuel Gilligan*

Post-mortem dismemberment is a disturbingly rare crime that can be committed for a variety of motives, including gratification from sexual activity, retaliation, or rage. The perpetrator may also raise the defense of insanity in some instances. The effectiveness of the insanity defense in cases involving post-mortem dismemberment is examined in this paper, as are the variables that may contribute to it. It involves discussing the delicate balance between providing justice for the victim and ensuring a fair assessment of the defendant's mental capacity. The study will delve into the potential conflicts between public perceptions, legal precedents, and mental health expertise, with the aim of highlighting areas where improvements in the legal system may be necessary. Ultimately, this research aims to contribute to the existing body of knowledge surrounding post-mortem dismemberment cases and the insanity defense.

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