Troubles neurologiques

What Most Influence Quality of Sleep in Parkinson’s Disease Patients?

Abstract

Svetlana Tomic, Marina Hlavati, Marta Petek, Mirjana Cubra, Tomislav Pucic, Tea Mirosevic Zubonja, Stjepan Juric, Anamarija Soldo Koruga, IvankaStenc Bradvica1 and Silva Butkovic Soldo

Study objective: Sleep disturbances are one of the most common non-motor symptoms of Parkinson´s disease that influence on the quality of life. Our aim was to investigate the incidence of sleep disturbances in patients with idiopathic Parkinson Disease and to evaluate what type of sleep disturbance influence most on the quality of the sleep in these patients.

Methods: One hundred and four Parkinson Disease patients treated in the University Hospital Centre Osijek and General Hospital Nasice were analysed. The patients were assessed with regards to whether or not they were experiencing sleep disturbances and were divided accordingly into two groups: those that did not have sleep disturbances and those that experienced sleep disturbances. All of the patients completed Parkinson Disease Sleep Scale.

Results: Sleep disturbance was reported in 58% patients, while 42% did not report to have sleep disturbance. Sleep disturbances group recorded lower mean result in Parkinson Disease Sleep Scale as well as lower mean results for each sub-scale for all symptoms except incontinence due to immobility compared to group with no sleep disturbances. We found statistically significant difference between two groups of patients on these items: quality of sleep (t=-3.046; p<0.005), maintenance of sleep (t=-2.869; p<0.005), distressing dreams (t=-2.947; p<0.005) and fatigue (t=-2.494; p<0.01). Regresion logistic analysis predict sleep disturbances significantly (omnibus chi-square=41,387, df=17, p<.001) with quality of sleep, distressing dreams and painful posturing as most predictive variable for sleep disturbances in SD group.

Conclusion: Nocturnal awakening, distressing dreams and fatigue influence most on the quality of sleep in patients with Parkinson´s disease. Variables that proved to be most significant predictors for sleep disturbance of PDSS are quality of sleep, distressing dreams and painful posturing