Revue des arts et des sciences sociales

The Effect of PCV13 Vaccination and Demographic Changes on the Future Pneumococcal Disease Burden in Germany: An Integrated Probabilistic Differential Equation Approach

Abstract

Myka Vanella

Pneumococcal disease is a significant cause of morbidity and mortality worldwide, including in Germany. The introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) has led to a reduction in pneumococcal disease burden. However, demographic changes, such as an aging population, can influence the future disease burden. This study aims to assess the combined effect of PCV13 vaccination and demographic changes on the future pneumococcal disease burden in Germany using an integrated probabilistic differential equation approach.