Journal de cosmétologie et de trichologie

Skin Aspartate Protease - A Key enzyme in Stratum Corneum Barrier Properties

Abstract

Mark Donovan

Human skin is a multi-layered tissue composed of three dynamic compartments, the epidermis, the dermis and the hypodermis. The outermost of these – the epidermis terminally differentiates to form the cornified layer – the stratum corneum- that has beautifully evolved to be an effective and impermeable barrier, providing us with watertight skin and a protective shield, which allows us to tolerate and live in all sorts of climatic and environmental conditions.