Troubles neurologiques

Silver Staining of Alzheimer's Disease

Abstract

Orwa Aboud and Sue T. Griffin W

Sliver stain of olfactory bulb tissue section in a 74 year old male with a clinical history of Alzheimer’s, congestive heart failure, and pneumonia. A. A 10X magnification for the area containing the anterior olfactory nucleus (AON) (astercs). B. A 20X of the same area showing neurofibrillary tangles (arrow) and neuropil threads (double arrow). The autopsy showed definite Alzheimer’s disease (C on CERAD scale). Neuritic plaques identified in inferior parietal and parahippocampal areas from this patient. There were moderate tangles in peristriate and frontal cortex, and neuropil threads were prominent in mesial temporal structures and frontal cortex.