Immunochimie et immunopathologie

Role of Systemic Immune Response in the Development of Cutaneous Leishmaniasis

Abstract

Tind Teleria*

This review provides a comprehensive overview of the systemic immune response in the context of CL pathogenesis, highlighting key immunological factors implicated in disease progression and outcome. Through a synthesis of current literature, this review elucidates the dynamic interactions between innate and adaptive immune components, cytokine networks and immune evasion mechanisms employed by Leishmania parasites. Insights gained from understanding the systemic immune response in CL not only contribute to our knowledge of parasitehost interactions but also offer potential avenues for the development of immunotherapeutic strategies and vaccines.