Toxicologie environnementale et analytique

Novel Applications of Micro Extraction Techniques Focused on Biological and Forensic Analyses

Abstract

Faisal Mohamed

In recent years, the main focus has been on microextraction methods that enable high recoveries of target analytes regardless of sample matrix complexity. The most commonly used techniques include liquid-liquid extraction (LLE), solid-phase extraction (SPE), solid-phase microextraction (SPME), dispersion-liquid microextraction (DLLME) and packed sorbent microextraction (MEPS) and bulk phase sorption extraction (FPSE). These techniques represent the rapid development of sample preparation techniques in various fields such as: B. Biology, Environment, Food Science, Natural Products, Forensics, Toxicology. In the fields of biology and forensics, where different drugs with different chemical properties are analyzed, sample preparation is required to make the samples suitable for instrumental analysis. Mass detector or tandem mass detector (MS/ MS). This review focused on the biological and forensic applications of these innovative techniques and highlighted the main benefits and results achieved in laboratory and clinical practice.