Chimie médicale

Nanoemulsion Based Targeting in Cancer Therapeutics

Abstract

Gannu Praveen Kumar and Ajmeera Divya

The major targeting strategies that were used for the delivery of therapeutics which are explored for many of the reported nanoemulsions suggest the great potential of targeted delivery to revolutionize cancer treatment. Targeted delivery via selective cellular markers can potentially increase the efficacy and reduce the toxicity of therapeutic agents. The effectiveness of a cancer therapeutic device is measured by its ability to reduce and eliminate tumors without damaging healthy tissue. Therefore, a distinct capacity to target tumors is essential in the success of the therapeutic device. An increased site specificity and internalization can improve the efficacy of treatment and decrease the possibility of the serious side effects that cancer patients often experience. The ultimate goal of cancer therapeutics is to increase the survival time and the quality of life of the patient. Nanoemulsions offer major improvements in therapeutics through site specificity, their ability to escape from multi-drug resistance and the efficient delivery of an agent. There is large overlap between the divisions which reflect the heterogeneity of tumor biology and the large potential for multiple targeting schemes using different ligands. The objective of this review is to outline current major cancer targets for nanoemulsions and give insight into the direction of the field.