Journal des maladies et soins respiratoires cliniques : accès libre

Investigating the Relationship between Asthma and Hemoglobinopathies

Abstract

Victor Braga

Asthma and hemoglobinopathies are distinct medical conditions that significantly impact public health worldwide. Asthma, a chronic inflammatory disease of the airways, affects millions of people, leading to considerable morbidity and healthcare costs. Hemoglobinopathies, including sickle cell disease and thalassemia, are inherited blood disorders that alter the structure or production of hemoglobin. Emerging evidence suggests an interplay between these two conditions, with potential implications for diagnosis, management, and patient outcomes. This review explores the relationship between asthma and hemoglobinopathies, examining epidemiological data, pathophysiological mechanisms, clinical manifestations, and therapeutic strategies.