Alessandro Gemma
Pediatric infections pose significant challenges due to the limited options for antimicrobial therapies, concerns about antibiotic resistance, and potential adverse effects on child development. In response, researchers are exploring alternative antimicrobial irrigation strategies to effectively treat infections in children while minimizing these risks. This abstract provides an overview of promising approaches in this emerging field. Firstly, probiotic irrigation presents a novel approach by harnessing the beneficial effects of probiotic bacteria to restore microbial balance in pediatric infections. Probiotics can outcompete pathogens and modulate immune responses, offering a targeted and potentially safer alternative to traditional antibiotics. Secondly, nanoparticle-based irrigation holds promise for its antimicrobial properties and targeted action. Nanoparticles, such as silver nanoparticles, exhibit potent antimicrobial activity against a wide range of pathogens while minimizing systemic side effects. Incorporating nanoparticles into irrigation solutions could offer a targeted and efficient treatment option for pediatric infections.
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