Troubles neurologiques

A Case of HLA-B27-Associated Optic Neuritis

Abstract

Matar A, Ibrikji S and Bou Ghannam Alaa*

We report the case of a young woman who presented with chronic relapsing inflammatory optic neuritis (CRION) in association with HLA-B27 and silent brain lesions. The attacks were refractory to steroids but no further attacks occurred on treatment with mycophenolate mofetil. This is one of the few HLA-B27- associated optic neuritis cases reported in the literature, emphasizing the relation of HLA-B27 and inflammation of the brain and optic nerve, as well as the role mycophenolate mofetil might offer in stabilizing the disease.